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At 24 hours the plasma levels of sildenafil ended up even now around 200 ng/mL, when compared with about 5 ng/mL when sildenafil was dosed by yourself. That is in keeping with ritonavir's marked outcomes on the wide selection of P450 substrates. VIAGRA had no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS]